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Questions discussed in this category

Would you start anticoagulation in a patient with a history of CVA 1 year ago and high risk APL profile who was never started on anticoagulation, but is now presenting for follow up and without recurrent thrombotic events?
The patient has no known history of autoimmune disease.
4 Answers available
What is your first line treatment for a patient with epilepsy who is homeless and has a history of poor adherence?
2 Answers available
What is your approach to treatment of benign fasciculation syndrome?
1 Answer available
How slowly do you taper a dopamine agonist to prevent dopamine agonist withdrawal syndrome (DAWS)?
6 Answers available
If you have a patient with isolated CN VII palsy (Bell's Palsy), and straightforward symptoms with no red flags (such as concern for carcinomatous meningitis), do you routinely get an MRI brain or do you just make a clinical diagnosis?
2 Answers available
Is LP indicated for patients with recurrent thunderclap headaches over a 4-week period and negative head imaging for SAH?
2 Answers available
How do you approach a patient with atrial fibrillation on Apixaban who has a new cardioembolic stroke?
3 Answers available
When do you consider prescribing medications such as Aricept in patients with Down Syndrome who start having memory issues?
2 Answers available
How frequently do you check AED levels in patients with stable epilepsy?
4 Answers available
Do you typically consider Botox for patients with TMJ?
4 Answers available
Which triptans do you use in stroke induced migraines?
Which triptans are safer in stroke induced migraines?
1 Answer available
Do you treat patients with riluzole who have ALS and a valosin-containing protein mutation?
Does your management change in any way?
1 Answer available
Is there a risk of CYP2C19 gene testing only being adopted by wealthier health systems, thereby creating a disparity gap in treatment?
What is the cost and accessibility of CYP2C19 gene testing? Does the limited availability of rapid genotyping techniques limit the clinical applicabil...
3 Answers available
Does the overall conclusion of the CHANCE-2 trial make ticagrelor + ASA a worthwhile transition given the data showing cumulative hazard of stroke diverged during the first week and was subsequently similar, which suggests the benefit of ticagrelor over clopidogrel is seen predominantly soon after stroke?
4 Answers available
When do you consider tapering tocilizumab in patients with GCA in remission?
1 Answer available
Do you ever do surveillance MR imaging in patients with stable exam and history of cardioembolic stroke?
1 Answer available
When do you use levocarnitine in patients on Depakote therapy for seizures
1 Answer available
How do you decide on initiation of treatment with steroids or immunomodulatory therapy in patients with statin-induced myopathy versus statin-induced autoimmune necrotizing myopathy?
In patients presenting with likely statin-induced myopathy versus statin-induced autoimmune necrotizing myopathy - how do you approach the decision re...
3 Answers available
What is your surveillance strategy in patients with brain metastases who are getting systemic therapy?
How often are you scanning the brain and what is your trigger to treat?
3 Answers available
What is your decision process on decreasing the sodium goal for patients with cerebral edema?
1 Answer available
How do you counsel young adults with antibody-negative necrotizing myopathy on prognosis and long-term monitoring/treatment?
How do you counsel young adults with antibody-negative necrotizing myopathy on prognosis, risk of recurrence, and long-term monitoring/treatment?
1 Answer available
Would you generalize the data from the CHANCE-2 trial to a broader clinic population given that the study was specific to Han Chinese patients?
How do you plan to incorporate the results of the CHANCE-2 trial (Wang et al., PMID 34708996) in your own practice?
3 Answers available
Do you recommend genetic testing after a patient on clopidogrel has a stroke based on the results of the CHANCE-2 trial?
3 Answers available
How do you manage tinnitus in patients with intracranial hypotension?
What is the etiology/pathology for tinnitus in Intracranial hypotension? How often is this symptom encountered in patients with intracranial hypotensi...
1 Answer available
Do you ever use IVIG in patients with parsonage-turner syndrome?
1 Answer available
Do you use vitamin B6 to help with keppra irritability?
6 Answers available
Would you consider anticoagulation for a young patient with a recent embolic stroke and newly diagnosed global cardiac hypokinesis with ejection fraction of less than 25%?
No thrombus detected on echocardiogram and no evidence of atrial fibrillation is present.
1 Answer available
Do you maintain an age cutoff for the use of triptans in healthy older patients without cardiovascular risk factors?
Do you perform routine screening for coronary artery disease in aging patients already taking these therapies?
1 Answer available
For patients with MS on natalizumab, at what JC virus antibody titer do you consider switching DMTs?
3 Answers available
When do you prescribe a steroid taper after the high dose IV course for a multiple sclerosis exacerbation?
3 Answers available
Do you recommend antiplatelet therapy for patients who have suffered stroke due to CADASIL?
3 Answers available
What workup do you do for patients who have PL-7 elevation when screening for myopathy?
2 Answers available
In a patient with presumed autoimmune encephalitis, would treating them with IVIG prior to getting a brain biopsy alter the pathological changes in a meaningful way?
1 Answer available
When do you pursue MR imaging in patients who present for migraine evaluation?
1 Answer available
How do you switch/cross-titrate regular Levodopa to Rytary in a patient with Parkinson's disease?
1 Answer available
Does the presence and location of cerebral microbleeds affect your decision for antithrombotic treatment in patients with atrial fibrillation?
Do you distinguish between primary and secondary prevention? Wilson et al., PMID 31130428 is helpful, but curious how people apply this data in practi...
3 Answers available
When do you consider plasmapheresis instead of (or in addition to) IV steroids for patients with acute MS exacerbation?
1 Answer available
Would you recommend short-term dual antiplatelet therapy for a patient who received tPA, and is otherwise eligible for dual antiplatelet therapy per POINT or SAMMPRIS trial?
3 Answers available
How do you evaluate asymptomatic patients referred for benign intracranial hypertension?
If patients are asymptomatic, what work up do you typically proceed with?
3 Answers available
When do you order an EMG for evaluation of patients with movement disorders?
Do EMG studies such as myoclonus or tremor studies change your management?
1 Answer available
How do you work up patients who present with elevated myoglobin in the setting of normal creatinine kinase and exercise intolerance?
For patients who present with elevated myoglobin in the setting of normal creatinine kinase and exercise intolerance, what work up process do you typi...
1 Answer available
When do you recommend driving tests in patients who have memory loss?
1 Answer available
When do you typically check vitamin B5 levels in patients with peripheral neuropathy?
B5 deficiency can be seen in patients with burning feet syndrome, do you typically screen for this when assessing for neuropathy?
2 Answers available
How do you interpret a mildly positive NT5C1A lab test in patients with hyperCKemia?
1 Answer available
How will you treat a young man with recurrent cryptogenic strokes with no identifiable cause, with MTHFR A1298C homozygous mutation and normal homocysteine level?
0 Answers available
Do you always initiate hypercoagulable work up in a patient with recurrent stroke?
If so, what would you consider ordering?
1 Answer available
How do you counsel patients interested in estrogen containing oral contraceptives who have migraine with aura?
4 Answers available
Are there certain sedatives or anti-epileptic meds to avoid in patients with IDD?
What are your thoughts on the ethics of inpatient use of sedatives in these patients to help with agitation to “protect themselves from harm and...
4 Answers available
Do you always pursue stroke work up in patients diagnosed with transient global amnesia?
For patients clinically presenting with Transient Global Amnesia and no other focal neurologic deficits, do you always pursue work up to rule out stro...
8 Answers available
How would you approach the treatment of checkpoint inhibitor mediated temporal arteritis?
Is there role for IVIG? Would you alter the dose or time course of steroid therapy?
2 Answers available
What holistic treatments do you recommend for patients with migraine without aura?
Which holistic treatments for migraine without aura do you recommend for patients who are refractory to standard treatments? 
1 Answer available
What is your preferred first line treatment for chronic fatigue in patients with long Covid?
3 Answers available
How do you counsel patients on anti-seizure medication necessity (or lack thereof) in the setting of PNES without comorbid epilepsy?
Occasionally, patients referred for dedicated epilepsy management for "medication refractory epilepsy" are found to have purely non-epileptic spells. ...
2 Answers available
How do you manage the developmental and behavioral regression seen in Down Syndrome Disintegrative Disorder (DSDD)?
1 Answer available
What workup do you recommend for patients with low back pain and imaging concerning for spina bifida occulta?
What referrals do you recommend/imaging orders?
1 Answer available
How do you approach DMT choice in a patient with MS with a history of cancer?
Based on this review (https://doi.org/10.3389/fimmu.2019.02954), patients with MS on several DMTs may be at higher risk for certain cancers. How does ...
1 Answer available
Do you counsel patients against driving who presents with transient global amnesia?
1 Answer available
What is your approach for a patient with an acute ischemic stroke caused by an aortic thrombus?
2 Answers available
How would you approach protein S deficiency found on hypercoagulability work-up in a patient with a post-operative central retinal vein occlusion?
In the setting of no personal or family history and no other risk factors for thrombosis, is systemic anticoagulation warranted if local treatments (e...
4 Answers available
Are adults with IDD at increased risk for adverse events like NMS or central anticholinergic syndrome?
1 Answer available
At what point do you consider implantation of a baclofen pump in patients with cerebral palsy?
1 Answer available
What monitoring do you routinely perform on lifelong EDS for epilepsy syndromes?
1 Answer available
What are your recommendations for screening for sleep disorders in patients with IDD?
Since these patients or their caregivers may not know the symptoms related to sleep disorders and the negative effects on their already compromised ne...
1 Answer available
Do you often encounter compressive neuropathies such as carpal tunnel syndrome in patients with spastic cerebral palsy?
1 Answer available
How do you counsel patients on driving who have PNEA?
5 Answers available
At what point do you recommend muscle biopsy in the workup for myositis?
1 Answer available
For patients with generalized tonic-clonic seizures lasting > 2 minutes without IV access, what alternative medications can be used?
1 Answer available
How does the FDA safety warning on the cardiac effects of lamotrigine, based on in vitro data, inform your clinical practice?
This question is intended to include consideration of cardiac diagnostic screening, as well as initiation & maintenance of lamotrigine, in epileps...
1 Answer available
When would you recommend standard of care over hypofractionated treatment in an elderly patient diagnosed with Glioblastoma?
1 Answer available
Do you routinely obtain an EEG in patients who are admitted with traumatic intra-cerebral hemorrhage?
3 Answers available
How do you treat medically refractory sleep related movement disorders?
How do you treat medically refractory sleep related movement disorder in patients who has failed medical management with dopamine agonists, gabapentin...
0 Answers available
How do you sequence pharmacologic treatments for primary insomnia?
2 Answers available
How do you manage acute exacerbations of trigeminal neuralgia?
What effective modalities have you found for acute exacerbations of trigeminal neuralgia including in patients who present to the ED? 
3 Answers available
How long after starting anticoagulation would you remove an IVC filter in a patient with a DVT presenting with stroke and PFO which is now closed?
1 Answer available
How do you taper off Clonazepam in women with epilepsy who are family planning?
How can one safely taper off and stop clonazepam in a woman of reproductive age with epilepsy who is taking it chronically for epilepsy and is plannin...
1 Answer available
What duration of dual antiplatelet therapy do you use for secondary prevention of ischemic stroke due to intracranial atherosclerotic disease?
While some have the practice of 90 days per SAMMPRIS, the lower rates of ischemic stroke in the medical therapy group were driven by events within the...
8 Answers available
In what conditions can you see roving eye movements?
1 Answer available
Is there any evidence that radiotherapy can worsen balance, dizziness, or vertigo in patients treated for vestibular schwannoma due to transient edema?
If so, what percent likelihood do you quote patients for this risk with SRS, SRT and fully fractionated therapy?
2 Answers available
Do you discourage patients from skydiving/roller coasters with a Chiari malformation?
1 Answer available
When would you add acyclovir for treatment of Bell's Palsy in addition to steroids and symptomatic care?
1 Answer available
In what patients would you consider adjunctive IVIG for Sjogren's-related neuropathy?
2 Answers available
How do you manage TTFields for a patient with glioblastoma in the setting of disease progression?
Do you routinely discontinue the device or continue if they are otherwise tolerating the treatment well? 
1 Answer available
What are your top takeaways from AAN 2022?
3 Answers available
How do you manage a patient with giant cell arteritis treated with weekly tocilizumab and low dose glucocorticoid who develops sudden vision loss?
2 Answers available
How do you complete brain death testing in patients who cannot tolerate apnea testing and are unable to transport for ancillary testing?
For instance, if the patient doesn’t tolerate apnea testing, is too unstable to go for ancillary testing outside the ICU, and TCDs/EEG are unava...
3 Answers available
What is your approach to a patient who has an ischemic stroke while on clopidogrel despite strict compliance and normal results on clopidogrel response assay?
5 Answers available
How do you manage patients with a diagnosis of AIDP who do not respond to initial IVIg?
3 Answers available
How long do you continue immunotherapy (ie rituximab) in patients with NMDAR encephalitis with initially severe disease but a good trajectory of recovery?
1 Answer available
How do you approach the management of Holmes tremor?
1 Answer available
When should we order a DaT scan in patients suspected of Parkinsonism syndrome?
When should we consider getting DaT scan in patient suspecting of Parkinsonism syndrome? 
2 Answers available
Would you consider spinal cord biopsy for an intramedullary cord lesion with disabling neurological deficits and no diagnosis despite a comprehensive workup?
What is the diagnostic yield and complication rate in your experience? 
2 Answers available
How do you decide between TCAR vs. carotid stenting for patients unstable for CEA?
2 Answers available
Can giant cell arteritis present with a partial cranial neuropathy?
3 Answers available
How do you approach the treatment of SREAT (steroid-responsive encephalopathy with autoimmune thyroiditis) after initial pulse dose steroids?
1 Answer available
When do you start anticoagulation in a patient with cardioembolic CVA secondary to new onset atrial fibrillation with hemorrhagic conversion?
1 Answer available
What is the dose conversion formula from botulinum toxin type B (Myobloc®) to incobotulinum toxin type A (Xeomin®) or onabotulinum toxin type A (Botox®)?
2 Answers available
When do you send AChR+ ocular myasthenia gravis patients for thymectomy?
How do you decide if and when to send patients with AChR+ ocular myasthenia gravis for thymectomy?
1 Answer available
What is your approach to the treatment of PML-IRIS in patients with HIV who have progressed to AIDS?
1 Answer available
How does evidence of cerebral amyloid angiopathy/microbleeds affect choices for secondary stroke prevention in patients with a history of ischemic stroke and atrial fibrillation?
How do you approach secondary stroke prevention for patients with ischemic stroke, atrial fibrillation, and signs of cerebral amyloid angiopathy/micro...
1 Answer available
How do you determine timing and frequency of stability scans for a patient with spontaneous, non-aneurysmal intracerebral hemorrhage?
What factors influence your thinking?
1 Answer available
What schedule and type of antiemetics do you provide for patients receiving PCV for co-deleted oligodendrogliomas?
1 Answer available
How often do you monitor CD-19 counts and immunoglobulin levels in MS patients on B-cell depletion therapy?
How do you approach low IgG levels on these medications?
2 Answers available
How do you approach the management of patients on lamotrigine who develop a minor rash?
Should one restart lamotrigine or look for an alternative? If no other alternative available, is slow titration vs regular titration preferred?
4 Answers available
Would you recommend medical therapy for asymptomatic idiopathic intracranial hypertension with completely normal visual field testing?
2 Answers available
Would you favor restarting anticoagulation or pursuing left atrial appendage closure in a patient with hemorrhagic stroke on anticoagulation for non-valvular atrial fibrillation?
3 Answers available
When do you use plasmapheresis after IVIG in patients with Guillain-Barre Syndrome?
4 Answers available
How do you approach the management of patients with one clinical demyelinating event and MOG+ antibody status?
Do you wait for a second clinical event or start immunomodulatory therapy right away?
3 Answers available
How do you manage Botox injections in patients with cervical dystonia after getting implanted with DBS?
How do you manage botulinum toxin injections in a patient with cervical dystonia after getting implanted with DBS?
1 Answer available
How do you acutely manage a free-floating thrombus in a major artery in a patient with a stroke as a result of it?
4 Answers available
What is your practice for the timing of resumption of oral anticoagulation after ICH?
Do you order any imaging beforehand? Are there other studies that you order?  
1 Answer available
What is your preferred approach to a pregnant patient in status migrainosus refractory to first line treatments?
What is your preferred approach to a pregnant patient who is in status migrainosus that is refractory to first line treatments?  
2 Answers available
Do you take any special precautions when treating cervical spine metastases?
Do you require neurosurgical evaluation first? Do you require any patients to wear a neck brace?  
1 Answer available
How do you approach pain management in patients with idiopathic polyneuropathy?
3 Answers available
When would you suspect metabolic myopathy and what is your approach to initial workup?
2 Answers available
How do you approach the timing of COVID-19 vaccination for patients with multiple sclerosis on B-cell depleting therapies?
3 Answers available
How do you treat behavioral disturbances in patients with dementia with Lewy bodies?
How do you treat dangerous behavioral disturbances (aggression, nighttime wandering) in patients with dementia with Lewy bodies (DLB)?
1 Answer available
How do you manage patients with chronic migraine as well as medication overuse headaches?
In patients with chronic migraine and possible medication overuse headache due to chronic narcotic use, what’s your strategy for those patients?...
5 Answers available
What are the best treatment options for persistent post-traumatic headaches when first line agents like TCAs have failed?
4 Answers available
For patients with significant side effects to a cholinesterase inhibitor, do you try another medication in the class or avoid it altogether?
If you have significant side effects, GI and/or cardiac with one of the cholinesterase inhibitors, would you try using another medication or would you...
1 Answer available
Do you use pimavanserin to treat psychotic symptoms in Lewy body dementia?
1 Answer available
What are some alternatives to dexamethasone for brain edema in patients who are allergic, have an intolerance, or refuse the medication?
5 Answers available
Do you frequently encounter asterixis in patients with UTI associated encephalopathy?
The most frequently taught cause of asterixis is hepatopathy and of course hepatic encephalopathy, and has other close associations (ie, uremia), I ha...
2 Answers available
When do you consider starting an anticholinergic in patients with tremor-predominant Parkinson's disease?
1 Answer available
How do you manage patients with Parkinson's disease when dopaminergic therapy worsens the freezing phenomenon?
How do you manage freezing of gait in Parkinson disease when dopaminergic therapy worsens the freezing phenomenon?
1 Answer available
What are the best options for resistant cases of ET?
What are the best options for resistant cases of ET?  Focused ultrasound or DBS?
4 Answers available
How do you approach the diagnosis and treatment of recurrent neurosyphilis in a previously treated patient?
Are VDRL titers useful?
1 Answer available
What is the role of x-ray of the cervical or lumbar spine in patients presenting with radicular symptoms?
I teach my students/residents that they should hardly ever get routine X-rays in patients presenting with radicular symptoms. MRI far better for seein...
4 Answers available
How do you approach the management of acute attacks of MOGAD-associated optic neuritis?
Specifically, what do you do if there is minimal improvement with IV steroids and/or IVIG?
2 Answers available
How do you choose between adjuvant PCV vs temozolomide in high risk oligodendroglioma with IDH mutation and 1p/19q co deletion ?
NCCN lists PCV as category 1 (and now with analysis in Abstract 2002 from ASCO 2019 showing benefit in IDH mutated), and temozolomide as 2B, yet temoz...
1 Answer available
Do you use a combination of anticoagulant and antiplatelet therapy for treating intraluminal internal cerebral artery thrombus causing stroke?
For what duration do you use therapy?
1 Answer available
How do you approach the management of a large vessel stroke if you anticipate the development of malignant cerebral edema?
Is there any benefit to starting hyperosmolar therapy prior to the development of depressed level of consciousness or midline shift?
1 Answer available
How do you manage neuropathic chemotherapy agents in patients with underlying multiple sclerosis?
Are there contraindications to drugs like oxaliplatin or abraxane? Does chronicity or severity of the patient's underlying symptoms play a role in yo...
1 Answer available
What would be the workup and the treatment of choice for isometric tremor?
Do you just see if the tremors are more associated with action versus static tremors? What are other clinical characteristics that can be helpful to c...
1 Answer available
How would you work up focal periventricular leukomalacia presenting in adulthood?
1 Answer available
When is it appropriate to use the 10mg-100mg Carbidopa/Levodopa formulation?
Is there a clinical scenario in which using the 10mg/100mg Carbidopa/Levodopa formulation is preferred to or more beneficial than using the more commo...
3 Answers available
How do you evaluate and treat patients with suspected POTS?
2 Answers available
How do you treat anti-HMGCoA myopathy?
3 Answers available
What is the most effective treatment for a patient with persistent post-stroke headache?
4 Answers available
Is unilateral intracranial EEG monitoring ever appropriate in the pre-surgical workup for presumed non-lesional epilepsy?
The thought being, if no clearly defined lesion exists on available neuroimaging, how do we balance the benefits, risks, and uncertainty in choosing w...
1 Answer available
Is vaginal delivery safe in patients diagnosed with pseudotumor cerebri (IIH)?
In patients diagnosed with pseudotumor cerebri, is vaginal delivery safe? How do you manage this condition during the pregnancy?
1 Answer available
How has your use of B-cell depleting therapy for MS changed during the COVID-19 pandemic?
Are there any specific patient populations that you are no longer routinely recommending to start B-cell depleting medications? For example, are you l...
1 Answer available
What is the first line therapy for demyelinating neuropathy with positive NF-155 antibodies?
1 Answer available
When do you redose IVIG in GBS patients who were under-treated and are worsening?
Is there any data supporting this?
2 Answers available
What AEDs prevent spikes and sharp waves?
3 Answers available
In those with a history of anti-NMDA encephalitis with identified teratoma s/p resection and clinical symptom improvement, is there a role for monitoring anti-NMDA antibody titer as a marker of disease recurrence?
1 Answer available
At what stage of the neuropathy workup do you screen for B6 toxicity?
2 Answers available
How do you treat lupus-associated small fiber neuropathy?
1 Answer available
Would you recommend PFO closure in patients >60 years old with presumed paradoxical embolism as their mechanism of stroke?
1 Answer available
Would it be prudent to complete long term cardiac monitoring (ie. 30 day) in a patient with a new typical appearing lacunar type thalamic infarct and history of hypertension?
1 Answer available
Is antiplatelet or anticoagulant therapy preferred for the secondary prophylaxis of cryptogenic stroke in a patient with underlying malignancy?
4 Answers available
Do you treat cerebral vein thrombosis with parenchymal hemorrhage using full dose heparin protocol rather than the high risk protocol?
1 Answer available
How do you manage drug-induced thrombocytopenia when the implicated drug is essential?
e.g. DITP from eptifibatide after a cardiac intervention
1 Answer available
What is the significance of elevated fractionated catecholamines in POTS?
What would be the next steps in these cases?
2 Answers available
Do you ever check antibodies against EBV as part of a workup for MS in a patient with white matter lesions of unclear etiology on MRI?
Based on the results of the recent longitudinal analysis linking EBV infection and MS (Bjornevik et al., PMID 35025605), can negative EBV antibodies (...
1 Answer available
What do you routinely recommend for non-pharmacologic management of essential tremor?
5 Answers available
What medication do you consider in patients who cannot take indomethacin or triptans with a diagnosis of Hemicrania Continua?
Is there data for CGRP inhibitors?
2 Answers available
When do you recommend neuropsychiatric testing in patients with post-concussive syndrome?
4 Answers available
How do you approach the symptomatic management of central vertigo in a patient with minimal improvement on (or contraindication to) meclizine?
1 Answer available
What are your recommendations for a patient with metastatic non-mutated lung adenocarcinoma who previously had headaches responsive to prednisone but with negative temporal artery biopsy for GCA?
For medical oncologists, would you offer a PD-1/L1 inhibitor? For other subspecialties, how would you counsel the oncologist regarding the risk of usi...
1 Answer available
Do you ever attribute oscillopsia to a cortical lesion?
1 Answer available
How do you approach the symptomatic management of Lhermitte's phenomenon in a patient with MS?
2 Answers available
How long do you maintain a patient with seropositive Neuromyelitis Optica Spectrum Disorder on disease modifying therapy?
For example, a clinically stable patient on eculizumab, do you continue it indefinitely?
1 Answer available
When tapering moderate to high doses of long term steroids do you routinely monitor for adrenal insufficiency?
Do you attempt to taper fully or maintain at a low dose?
2 Answers available
What features help distinguish thyroid myopathy from immune checkpoint inhibitor-associated myopathy?
1 Answer available
Do you start anticoagulation in a patient with infective endocarditis who also has atrial fibrillation and stroke ?
1 Answer available
What is the negative predictive value of a completely unremarkable EMU admission?
By completely unremarkable, I mean zero clinical events AND zero interictal abnormalities despite full withdrawal of medications. Assume, for the sake...
2 Answers available
How would you approach evaluation and treatment of a patient on pembrolizumab therapy who presents with symmetric, proximal, upper extremity and lower extremity painful weakness without an elevated CK?
1 Answer available
Is angioedema secondary to IV tPA considered an absolute contraindication for tPA in future?
3 Answers available
Have you seen patients who develop neuromuscular disorders following COVID-19 vaccination?
1 Answer available
In what clinical situations do you treat triphasic waves on EEG?
What are some high-yield instances where triphasic waves on electroencephalogram (EEG) are more than just harmless markers of gross toxic-metabolic en...
2 Answers available
What additional treatments do you offer to patients with Progressive Supranuclear Palsy other than a levodopa/carbidopa challenge?
1 Answer available
How do you approach the workup of a patient with incidentally found pachymeningitis?
1 Answer available
Do you recommend EMG/NCS in all patients with clinical findings of carpal tunnel syndrome?
4 Answers available
How do you approach transitioning MS patients from Ocrevus to Tysabri or vice versa?
1 Answer available
What conditions do you screen for in patients with hyperacusis?
2 Answers available
How do you approach the workup and management of patients with suspected functional neurologic disorders?
What testing do you typically proceed with?
1 Answer available
In what subset of traumatic brain injury/concussion patients would you consider use of N-Acetyl Cysteine?
2 Answers available
In which subset of patients with concussion do you recommend further brain imaging?
Do you typically recommend MRI or CT?
1 Answer available
What is the preferred management plan for patients diagnosed with a concussion in the acute setting?
1 Answer available
At what point is a skin biopsy indicated in patients with neuropathy?
1 Answer available
How do you manage and treat post stroke alien hand syndrome?
1 Answer available
How do you treat refractory focal status epilepticus in patients with traumatic bilateral subdural hematomas?
How do you treat refractory focal status epilepticus in an adult with history of alcoholism and traumatic bilateral subdural hematomas who is failing ...
1 Answer available
Do you always perform temporal artery biopsy in patients with positive inflammatory markers and high clinical suspicion of GCA?
2 Answers available
Is either ESR or CRP more sensitive or specific for the diagnosis of GCA?
Additionally, what is the current role for temporal artery ultrasound in workup for GCA?
3 Answers available
How do you prescribe Perampanel for use in patients with refractory status epilepticus?
What is the your preferred loading (and maintenance) dose for use of Perampanel in the treatment of refractory status epilepticus?
2 Answers available
How would you approach treatment of a brainstem AVM after hemorrhage in a patient not a candidate for surgery or embolization?
What would be your preferred technique and dose/fractionation?
2 Answers available
How do you treat post-IVIG headache that is not responsive to Tylenol or NSAIDs?
Specifically, how do you treat the delayed headache, not the headache that develops during the infusion where pre-hydration and slowing down the rate ...
4 Answers available
What is the utility in repeating a temporal ultrasound (US) in a previously US diagnosed positive GCA patient who has received treatment and is presenting with recurrent GCA symptoms?
1 Answer available
For patients with atrial fibrillation on DOAC, when should they resume DOAC after a thalamic bleed without intraventricular bleed?
How does presence of intraventricular hemorrhage change your recommendations?
2 Answers available
How do you evaluate and treat patients with cerebral edema secondary to hyperammonemia?
What modality do you prefer?
3 Answers available
When is brain biopsy useful/warranted as part of the diagnostic work-up in patients with suspected primary CNS angiitis?
3 Answers available
At what intervals do you obtain DEXA scans for patients on antiseizure medications?
The question is broad and is meant to include patients who have healthy BMD, osteopenia, and osteoporosis, as well as exposure to first generation AED...
1 Answer available
What is the appropriate workup and treatment for patients with SMART syndrome following radiation for brain tumors?
For stroke-like migraine attacks after radiation therapy (SMART syndrome), does your management of these patient's change with recurrent episodes? How...
1 Answer available
What is the best course of action for a patient with isolated carcinomatous meningitis who is responding well to intrathecal methotrexate but now has MRI findings suspicious for methotrexate leukoencephalopathy?
Can intrathecal methotrexate be continued with close neurologic observation vs switch in treatment now due to findings?
1 Answer available
Do you ever use bevacizumab in combination with standard radiation and temozolomide in the first-line setting for patients with glioblastoma?
If so, when do you consider this? 
1 Answer available
How do you manage a patient with inclusion body myositis?
Is there a role for immunomodulatory therapy?
2 Answers available
How do you approach patients with suspected CNS lymphoma who have been treated with steroids?
Do you biopsy immediately, stop treatment, biopsy at a later time, or depend solely on the data you already have?
1 Answer available
When is follow-up imaging warranted in patients with anoxic brain injury?
What modality do you prefer?
1 Answer available
What abortive migraine treatment is preferred in pregnant patients?
1 Answer available
What workup do you recommend for patients with stabbing headaches?
How do you approach treatment?
1 Answer available
What symptomatic management do you recommend in patients with post LP headaches?
When do you consider a blood patch? 
1 Answer available
What DHE migraine protocol works best for acute treatment both in terms of dosage and timeframe?
1 Answer available
What is the importance of finding a positive titer for FGFR3 and what treatment would be advised for these patients?
1 Answer available
When do you initiate immunosuppressant drugs for patients with a diagnosis of myasthenia gravis?
1 Answer available
What workup do you start in patients with evidence of demyelination on EMG/NCS?
At what point do you consider genetic testing?
1 Answer available
Do you start Riluzole on all patients diagnosed with ALS?
Are there any reasons you avoid therapy?
2 Answers available
When would you consider treatment with steroids in patients with diabetic radiculoplexus neuropathy?
Are there any alternative treatments?
1 Answer available
How do you manage a symptomatic meningioma and associated vasogenic edema in a poor performance status patient?
Is there any additional benefit to radiation in addition to steroids in a patient who is not a surgical candidate?
2 Answers available
How do you modify TNBC neoadjuvant chemotherapy in patients with multiple sclerosis?
1 Answer available
When do you consider deep brain stimulation in patients with Huntington's disease?
Given the bleak prognosis in HD, how do you decide which patients will benefit from DBS to treat the chorea?
1 Answer available
When do you consider middle meningeal artery embolization in patients with recurrent subdural hemorrhages?
In what clinical scenario would you refer a patient for embolization? Are there any contraindications? 
1 Answer available
When would you consider checking JC virus prior to initiating biologic therapy?
1 Answer available
What treatment modalities do you offer patients who have ataxia?
Especially forms of non-pharmacologic treatment, such as physical therapy or special devices.
0 Answers available
How do you manage multiple cavernous malformations that have bled and enlarged over time?
1 Answer available
For patients with a new diagnosis of active secondary progressive multiple sclerosis (SPMS) without prior trials of disease-modifying therapy, do you treat with siponimod or do you start with a different DMT?
1 Answer available
Do you recommend work up for POEMS and/or amyloidosis for IgM monoclonal gammopathies associated with neuropathy?
Can you expand on this by sharing exactly what this routine workup should include? What additional tests outside of evaluating for POEMS and amyloidos...
2 Answers available
What treatment strategies do you employ in patients with Huntington's disease who have parkinsonian features?
1 Answer available
At what timepoint do you do an EMG/NCS in patients with suspected GBS?
How long do you wait (from onset of symptoms) to do a EMG/NCS in a patient with GBS?
1 Answer available
How to you treat pregnant women who develop Bell's Palsy?
1 Answer available
For which stroke patients, if any, do you recommend implantable loop recorder for long-term cardiac monitoring and why?
It seems clear that longer monitoring yields more AF detected. What is less clear to me is whether all ILR-detected AF is relevant and merits anticoag...
1 Answer available
How do you differentiate motor neuron disease from limb girdle muscular dystrophy on electrodiagnostic testing?
What other workup/clinical examination findings do you look for?
1 Answer available
In a patient with suspected Miller Fisher syndrome, would you wait until antibody testing results to start IVIG or treat empirically?
Is there is a particular pattern of extraocular motility restriction in Miller Fisher syndrome? 
1 Answer available
Which method do you prefer to assess for stigmata of old optic neuropathy, optical coherence tomography, or visual-evoked potentials?
1 Answer available
How do you manage orthostatic hypotension in patients with Parkinsonian syndromes?
We often use abdominal binders and compression stockings, in addition to hydration and midodrine/fludricortisone. However, are there more targeted the...
4 Answers available
When do you consider a levodopa trial in patients with new-onset dystonia?
1 Answer available
How do you determine if a patient is safe to drive after having a PCA infarct?
What is the best way to determine if patients with new PCA territory infarct can drive? Upon discharge from the hospital, do you routinely refer them ...
1 Answer available
What is your steroid-sparing agent of choice to treat GCA given the current tocilizumab shortage?
Thoughts on sarilumab vs methotrexate, or just treat with steroids alone
1 Answer available
How do you treat patients with symptoms of acute ischemic stroke who have an allergic reaction to alteplase?
How would you treat patients with symptoms of AIS who have an allergic reaction to TPA with no evidence of large vessel occlusion on imaging? What nex...
1 Answer available
What is your approach to checking serum vWF antigen levels in adult patients with CNS vasculitis for monitoring disease activity?
Small study in pediatric PACNS have evaluated this as a potential marker (Cellucci et al., PMID 22740622)
1 Answer available
When do you start anticoagulation for secondary prevention in patients with HFrEF and history of embolic strokes?
For a relatively young, medically compliant patient with HFrEF (EF<35%) and h/o embolic stroke, what is the consensus of starting AC for secondary ...
1 Answer available
How do you manage ADHD in patients with Tourette syndrome?
How do you manage ADHD in patients with Tourette syndrome in order to prevent exacerbating the tics such as with medications like Aderall?
1 Answer available
What treatments would you recommend in patients with adult-onset Rasmussen’s encephalitis after the patient is on two or more AEDs?
Is there an AED of choice?
1 Answer available
For patients with ischemic stroke status-post decompressive hemi-craniectomy, when should they start aspirin for secondary stroke prevention?
For patients with ischemic stroke status-post decompressive hemi-craniectomy, when should they start aspirin for secondary stroke prevention? POD 5? P...
1 Answer available
How would you manage adjuvant endocrine therapy for a postmenopausal patient with early stage HR+ breast CA who develops an ischemic CVA on an AI?
Presuming that work-up for cardioembolic sources is negative, how would you proceed?
1 Answer available
Do you routinely recommend a sleep study in patients with clinical history of REM-sleep behavior disorder?
Does this add any value?
1 Answer available
How do you counsel patients on control of glioma-related seizures following radiation?
2 Answers available
How do you tailor seizure medications in patients who become pregnant or are family planning?
1 Answer available
How do you approach treatment of 1p19q non-codeleted high grade gliomas?
Has the recently published interim analysis of the CATNON trial altered your utilization of temozolomide? Does IDH status change your treatment appro...
1 Answer available
Is it ever appropriate to omit temozolomide in unmethylated glioblastoma?
Do you consider the small, but statistically significant, improvement in OS to outweigh the side effects of treatment?
3 Answers available
How do you approach a mildly positive finding on an autoimmune encephalitis panel when there is no other evidence of encephalitis (such as elevated CSF protein, abnormal neuroimaging, or EEG findings)?
For example, a GAD65 Ab of 0.07 when the cut-off is 0.02. Does this answer change if you consider adult vs pediatric populations?
2 Answers available
In what situation do you use nerve blocks in patients with headache?
1 Answer available
For patients with post-stroke headaches, what treatment do you typically recommend?
1 Answer available
How do you approach treatment of a glioblastoma in pregnancy?
3 Answers available
How do you manage incidentally identified pituitary lesions on brain imaging?
What workup do you typically recommend?
1 Answer available
Is placing a VP shunt a major risk to spread medulloblastoma or other malignant brain tumors into the gut?
1 Answer available
In a healthy patient >65 years of age with glioblastoma multiforme, what is the recommendation for temozolomide when given concurrently with adjuvant radiation therapy?
Length of temozolomide course when given with adjuvant radiotherapy
1 Answer available
In women of childbearing age with NMDA encephalitis and normal pelvic imaging, is there a role for oophorectomy for possible microteratoma?
If not, how often do you repeat pelvic imaging?
1 Answer available
In patients in the ICU who are on the inter-ictal continuum, how do you decide whether or not to treat for potential non-convulsive status epilepticus?
In patients undergoing continuous EEG monitoring in the ICU, we often encounter EEG patterns that lie along the inter-ictal continuum (IIC). In such c...
1 Answer available
How do you manage autonomic storming in patients with increased intracranial pressure?
1 Answer available
In patients with Duchenne Muscular Dystrophy who have an exon 51 mutation, do you treat with both prednisone and Eteplirsen?
What are common side effects to look out for with Eteplirsen?
1 Answer available
In patients with clinically probable ALS, what other mimicking pathology do you rule out before establishing the diagnosis?
Ie through electrodiagnostic, imaging, and otherwise?
2 Answers available
Do you recommend pre-emptive anti-epileptic treatment for patients with spontaneous ICH?
If so, for how long?
3 Answers available
When do you consider discontinuing disease modifying therapies for multiple sclerosis?
1 Answer available
Would you recommend a CGRP inhibitor for migraine prevention in pregnant patients?
Are there contra-indications while breast-feeding?
1 Answer available
At what point could starting AEDs be considered for patients with recurrent simple febrile seizures?
What steps should be taken to wean them off?
1 Answer available
When is the best time to consider left atrial appendage closure for secondary stroke prevention in patients with atrial fibrillation?
For example, with a Watchman device? What is the evidence behind this?
1 Answer available
How do you approach the management of poorly controlled migraines during pregnancy?
1 Answer available
At what point do you refer patients with medication refractory epilepsy for surgical evaluation?
2 Answers available
When do you consider lesion therapy (such as pallidotomy or subthalamotomy) instead of DBS in patients with Parkinson's disease?
1 Answer available
How do you approach the diagnosis of MS subtypes like Balo's concentric sclerosis?
Do you approach things differently if a rare variant like this is suspected? Is the Balo's subtype more similar to RRMS or PPMS?
1 Answer available
How do you treat paroxysmal phenomena such as paroxysmal dysarthria or dyskinesia in multiple sclerosis?
1 Answer available
What workup and management plan is indicated for patients with orthostatic tremor?
1 Answer available
How do you manage random-OFF periods in patients with Parkinson's disease who are otherwise having good control of their motor symptoms?
1 Answer available
How would you manage leptomeningeal disease of the spine in the setting of prior WBRT?
What factors play into your decision whether to re-treat the brain with craniospinal radiotherapy vs irradiation of the spine only vs other measures (...
1 Answer available
When do you restart anticoagulation in patients with atrial fibrillation who just had an ischemic stroke?
1 Answer available
What is your approach for treating mononeuritis multiplex in patients with ANCA vasculitis?
Specifically, do you reach for Rituximab or cyclophosphamide?
1 Answer available
When do you consider starting hypertonic saline solution in patients with an acute ischemic stroke?
1 Answer available
How do you approach management of cerebral venous sinus thrombosis in a patient with severe thrombocytopenia?
1 Answer available
Is an EMG/NCS required to clinically diagnose Guillain barre syndrome?
1 Answer available
When do you trial pyridostigmine in a patient with suspected myasthenia gravis?
Is there a role for using a trial of pyridostigmine as a diagnostic aid in a patient with suspected (but not confirmed) myasthenia gravis?
1 Answer available
When do you recommend electrical stimulation (cephaly device) in patients with chronic migraine, if at all?
1 Answer available
How do you manage oxaliplatin-induced acute peripheral nerve hyperexcitability?
Patients can develop sensory and motor symptoms such as paresthesias, jaw/facial pain and stiffness, cramping and twitching, ptosis and vision changes...
2 Answers available
Should patients with clinically isolated syndrome be started on medication?
1 Answer available
Should patients who have had hemorrhagic strokes be restarted on oral anticoagulation?
If so, how do you decide when to restart anticoagulants?
1 Answer available
How do you determine the timing of anticoagulation for patients with large MCA strokes secondary to atrial fibrillation?
1 Answer available
Should patients with cerebral amyloid angiopathy have any statin medications discontinued?
1 Answer available
In what clinical settings is acute ICH clot removal recommended?
1 Answer available
In patients with recurrent ischemic infarcts on the same side as an internal carotid artery lesion, is intervention warranted even if there is less than 50% obstruction?
When would you consider stenting or CEA even if there is less than 50 obstruction when no other etiology has been found?
1 Answer available
How do you limit the onset of new strokes in patients with Moya-Moya syndrome?
1 Answer available
Would you consider using a TNFi in a patient with a family history of demyelinating disease, in the absence of a personal history?
2 Answers available
In what situations would you consider memantine when treating multiple brain metastases with SRS?
1 Answer available
How do you approach the use of biologics in patients with a history of Guillain-Barre syndrome?
1 Answer available
At what point is it warranted to send an autoimmune epilepsy panel in patients?
1 Answer available
When is a paraneoplastic panel indicated when working up patients with neuromuscular conditions?
0 Answers available
What is the importance of finding a positive titer for TS-HDS and what treatment would be advised for these patients?
2 Answers available
Are there features of a nerve biopsy that help distinguish late nerve damage from vasculitis versus from a demyelinating disease?
1 Answer available
What is the optimal management for a patient with Tourette Syndrome with severe tics that preclude the patient from lying still for radiation?
E.g. The case in question is for a patient planned for thoracic RT for LS-SCLC. Any medications that may help or just give much bigger expansions to c...
1 Answer available
How do you approach treatment of a spinal meningioma?
When do you favor RT? What is your preferred dose/fractionation?
1 Answer available
How do you do approach treatment of a recurrent gliosarcoma?
How does length of time from prior chemoradiotherapy influence your management?
1 Answer available
Do you treat HIV/AIDS-associated CNS vasculitis with antiretrovirals alone or in combination with steroids?
1 Answer available
How do you monitor response to treatment in patients with mononeuritis multiplex secondary to vasculitis?
Given the slow recovery of nerve damage, what would you expect to see on a repeat EMG after treatment? Continued denervation or just sequelae of past ...
1 Answer available
How do you manage cranial radiotherapy in the setting of an acute CVA?
In a palliative setting, how long would you wait to initiate WBRT?
1 Answer available
Is it safe to use statins in IIM patients if HMGCR antibodies are negative?
1 Answer available
Do you recommend getting a muscle biopsy in a patient with suspected IMNM with statin exposure, weakness, elevated CK, and positive HMGCR antibody?
2 Answers available
What steroid-sparing agent would you use for treatment of neurosarcoidosis with leptomeningeal and parenchymal involvement?
1 Answer available


Papers discussed in this category

Stroke, 2008 Jul 17
Establishing final infarct volume: stroke lesion evolution past 30 days is insignificant.
J Neuroimaging, 2020 Feb 10
From "Time is Brain" to "Imaging is Brain": A Paradigm Shift in the Management of Acute Ischemic Stroke.
The New England journal of medicine, 2014-02-20
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
The New England journal of medicine, 2014-02-20
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Neuro-oncology, 2016-09
Upfront bevacizumab may extend survival for glioblastoma patients who do not receive second-line therapy: an exploratory analysis of AVAglio.
Onco Targets Ther, 2017 Jan 18
Add-on bevacizumab can prevent early clinical deterioration and prolong survival in newly diagnosed partially resected glioblastoma patients with a poor performance status.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-01-20
Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402.
The New England journal of medicine, 2005-03-10
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
The New England journal of medicine, 2016-04-07
Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma.
J Clin Oncol, 2012 Oct 15
Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.
J Clin Oncol,
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.
Neuro Oncol, 2016 Jul 01
Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-04-01
Phase III randomized, placebo-controlled, double-blind study of intravenous calcium and magnesium to prevent oxaliplatin-induced sensory neurotoxicity (N08CB/Alliance).
Oncol Lett, 2015 Aug 11
FOLFIRINOX-induced reversible dysarthria: A case report and review of previous cases.
Neurology, 2016 Nov 16
Treatment of neurosarcoidosis: A comparative study of methotrexate and mycophenolate mofetil.
Clin. Chest Med., 2015 Sep 26
Neurosarcoidosis.
Clin. Exp. Rheumatol., 2013 Dec 09
Anti-TNF-α therapy in the management of severe neurosarcoidosis: a report of five cases from a single centre and literature review.
Pediatric emergency care, 2008-04
Clinical diagnosis of ventriculoperitoneal shunt failure among children with hydrocephalus.
Clin Nucl Med,
Extracranial Metastases From Glioblastoma With Primitive Neuronal Components on FDG PET/CT.
World J Surg Oncol, 2019 Mar 27
Clinical outcome of cerebrospinal fluid shunts in patients with leptomeningeal carcinomatosis.
Asian J Neurosurg,
Widespread Intra-abdominal Carcinomatosis from a Rhabdoid Meningioma after Placement of a Ventriculoperitoneal Shunt: A Case Report and Review of the Literature.
Journal of neurosurgery, 2005-09
Acute neurological complications following gamma knife surgery for vestibular schwannoma. Case report.
Surgical neurology, 2000-05
Acute complications following gamma knife radiosurgery are rare.
Cureus, 2020 Jun 11
Vestibular Migraine Following Radiosurgery for Vestibular Schwannoma.
Stereotact Funct Neurosurg, 2019 Nov 26
Symptomatic Post-Radiosurgery Intratumoral Hemorrhage in a Case of Vestibular Schwannoma: A Case Report and Review of the Literature.
N Engl J Med,
Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma.
Circulation, 2020 Feb 17
Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study.
Acta Oncol, 2015 Oct 23
Randomized phase II trial comparing twice daily hyperfractionated with once daily hypofractionated thoracic radiotherapy in limited disease small cell lung cancer.
Int J Radiat Oncol Biol Phys, 2020 Jun 13
Is There a Role for Hypofractionated Thoracic Radiation Therapy in Limited-Stage Small Cell Lung Cancer? A Propensity Score Matched Analysis.
Muscle & nerve, 2003-02
Sensory neuropathy with monoclonal IgM binding to a trisulfated heparin disaccharide.
Muscle & nerve, 2012-06
Clinical and laboratory features of neuropathies with serum IgM binding to TS-HDS.
Stroke, 2020 Aug 06
Anticoagulation Type and Early Recurrence in Cardioembolic Stroke: The IAC Study.
Mult Scler, 2018 Feb
2017 McDonald MS diagnostic criteria: Evidence-based revisions.
Neurology. Clinical practice, 2018-02
Anticoagulation for atrial fibrillation after intracranial hemorrhage: A systematic review.
Pediatrics, 2015-02
Benefits of strict rest after acute concussion: a randomized controlled trial.
Stroke, 2015 May 28
Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.
Neurology, 2016 Jan 08
Orthostatic tremor: Clinical, electrophysiologic, and treatment findings in 184 patients.
Sleep Med Rev, 2021 Jun 10
REM sleep behavior disorder: Mimics and variants.
Neuro-oncology, 2013-10
Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial.
Stroke, 2019-02
Ischemic Stroke and Internal Carotid Artery Web.
J Clin Rheumatol, 2021 Sep 23
Role of Intravenous Immunoglobulin in Necrotizing Autoimmune Myopathy.
The New England journal of medicine, 2015-10-22
Intravenous Immune Globulin for Statin-Triggered Autoimmune Myopathy.
Rheumatol Int, 2019 Feb 18
Intravenous human immunoglobulin and/or methylprednisolone pulse therapies as a possible treat-to-target strategy in immune-mediated necrotizing myopathies.
Arthritis and rheumatism, 2001-12
Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides.
Neurology, 2020 Jul 29
Effect of ocrelizumab on vaccine responses in patients with multiple sclerosis: The VELOCE study.
Cells, 2018 Dec 28
Ocrelizumab Depletes CD20⁺ T Cells in Multiple Sclerosis Patients.
Stroke, 2011-04
Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association.
Ann Neurol, 2020 Aug 05
Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk.
N. Engl. J. Med.,
Pembrolizumab for Early Triple-Negative Breast Cancer.
Pract Neurol, 2015 Jun 04
Diagnosing dopamine-responsive dystonias.
Neurotherapeutics,
The Medical Management of Cerebral Edema: Past, Present, and Future Therapies.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019-08
Treatment Approaches to Lacunar Stroke.
Stroke, 2021 Sep 14
Cilostazol for Secondary Stroke Prevention: History, Evidence, Limitations, and Possibilities.
Stroke, 2015-03
Outcome in patients previously on antithrombotic therapy in the SAMMPRIS trial: subgroup analysis.
BMJ open, 2014-12-02
Is clopidogrel better than aspirin following breakthrough strokes while on aspirin? A retrospective cohort study.
J Am Coll Cardiol,
Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial.
Neurol Sci, 2015 Jun 25
Balò's concentric sclerosis: still to be considered as a variant of multiple sclerosis?
World J Clin Cases,
Balo's concentric sclerosis in a patient with spontaneous remission based on magnetic resonance imaging: A case report and review of literature.
Annals of neurology, 2013-11
Eteplirsen for the treatment of Duchenne muscular dystrophy.
Acta Neurochir (Wien), 2019 Jan 29
Influence of pregnancy on glioma patients.
J. Clin. Oncol., 2020 Feb 14
Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001.
Cancer, 2020 May 19
Second cancer risk after primary cancer treatment with three-dimensional conformal, intensity-modulated, or proton beam radiation therapy.
Mult Scler Relat Disord, 2020 Dec 16
Interleukin-6 inhibition with tocilizumab for relapsing MOG-IgG associated disorder (MOGAD): A case-series and review.
N Engl J Med,
MGMT gene silencing and benefit from temozolomide in glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012-09-01
Randomized trial of radiation therapy plus procarbazine, lomustine, and vincristine chemotherapy for supratentorial adult low-grade glioma: initial results of RTOG 9802.
Lancet Oncol, 2021 May 14
Adjuvant and concurrent temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): second interim analysis of a randomised, open-label, phase 3 study.
Strahlenther Onkol,
Temozolomide combined with irradiation as postoperative treatment of primary glioblastoma multiforme. Phase I/II study.
Journal of neurosurgery, 2015-06
Pallidal stimulation for Holmes tremor: clinical outcomes and single-unit recordings in 4 cases.
Neurology, 2015-09-29
Dual antiplatelet therapy in stroke and ICAS: Subgroup analysis of CHANCE.
Stroke, 2017-08
Challenges in the Medical Management of Symptomatic Intracranial Stenosis in an Urban Setting.
Stroke, 2021 May 24
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association.
Lancet (London, England), 2014-01-25
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
Circulation, 2019-08-20
Time Course for Benefit and Risk of Clopidogrel and Aspirin After Acute Transient Ischemic Attack and Minor Ischemic Stroke.
Archives of neurology, 2009-06
Ganglionic acetylcholine receptor autoantibody: oncological, neurological, and serological accompaniments.
Muscle & nerve, 2013-04
Striational antibodies in a paraneoplastic context.
Muscle & nerve, 2016-08
P/Q- and N-type calcium-channel antibodies: Oncological, neurological, and serological accompaniments.
Muscle & nerve, 2017-07
GAD65 neurological autoimmunity.
Annals of neurology, 2017-07
Expanded phenotypes and outcomes among 256 LGI1/CASPR2-IgG-positive patients.
Headache, 2013-03
Expert consensus recommendations for the performance of peripheral nerve blocks for headaches--a narrative review.
Headache, 2021 Jun 23
The American Headache Society Consensus Statement: Update on integrating new migraine treatments into clinical practice.
J Neurol, 2021 Jul 17
Frequency of silent brain infarction in transient global amnesia.
Headache, 1990-05
Repetitive intravenous DHE in the treatment of refractory headache.
Neurology, 1986-07
Repetitive intravenous dihydroergotamine as therapy for intractable migraine.
Headache, 1997-03
Continuous intravenous dihydroergotamine in the treatment of intractable headache.
J Pain Res, 2020 Apr 30
Updated Evaluation of IV Dihydroergotamine (DHE) for Refractory Migraine: Patient Selection and Special Considerations.
Headache, 2010 Jan 28
Outpatient home-based continuous intravenous dihydroergotamine therapy for intractable migraine.
J Vasc Surg, 2019 Dec 31
Duration of blood flow reversal during transcarotid artery revascularization does not affect outcome.
Front Neurol, 2019 Jun 06
Primary Angiitis of the Central Nervous System: New Potential Imaging Techniques and Biomarkers in Blood and Cerebrospinal Fluid.
Headache, 2018-07
Spontaneous Intracranial Hypotension: 10 Myths and Misperceptions.
The New England journal of medicine, 2012-05-17
Warfarin and aspirin in patients with heart failure and sinus rhythm.
The New England journal of medicine, 2018-10-04
Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease.
The New England journal of medicine, 2019-05-16
Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source.
Heart, 2019 Apr 08
Anticoagulation therapy in heart failure and sinus rhythm: a systematic review and meta-analysis.
Lancet Neurol, 2018 Mar 07
Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study.
Neurology(R) neuroimmunology & neuroinflammation, 2017-07
Optical coherence tomography and visual evoked potentials in pediatric MS.
J Med Life,
Optical coherence tomography versus visual evoked potentials in detecting subclinical visual impairment in multiple sclerosis.
J Clin Neurol, 2018 Feb 28
Optical Coherence Tomography versus Visual Evoked Potentials for Detecting Visual Pathway Abnormalities in Patients with Neuromyelitis Optica Spectrum Disorder.
Mult Scler, 2014 Mar 03
Optical coherence tomography and visual evoked potentials: which is more sensitive in multiple sclerosis?
Mult Scler Relat Disord, 2016 Dec 23
Sensitivity of visual evoked potentials and spectral domain optical coherence tomography in early relapsing remitting multiple sclerosis.
N Engl J Med,
Trial of Tocilizumab in Giant-Cell Arteritis.
Lancet, 2016 Mar 04
Tocilizumab for induction and maintenance of remission in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial.
Arthritis Rheum,
Adjunctive methotrexate for treatment of giant cell arteritis: an individual patient data meta-analysis.
MedGenMed : Medscape general medicine, 2005-11-10
Management of idiopathic intracranial hypertension in pregnancy.
American heart journal, 2010-07
Cryptogenic Stroke and underlying Atrial Fibrillation (CRYSTAL AF): design and rationale.
Lancet, 2021 Aug 27
Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial.
Seminars in arthritis and rheumatism, 2012-06
Utility of erythrocyte sedimentation rate and C-reactive protein for the diagnosis of giant cell arteritis.
Arthritis Rheumatol, 2021 Jul 08
2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis and Takayasu Arteritis.
Ann Rheum Dis, 2019 Jul 03
2018 Update of the EULAR recommendations for the management of large vessel vasculitis.
International journal of radiation oncology, biology, physics, 2018-06-01
Radiation-Induced Edema After Single-Fraction or Multifraction Stereotactic Radiosurgery for Meningioma: A Critical Review.
Surgical neurology international, 2018
Role of bevacizumab for treatment-refractory meningiomas: A systematic analysis and literature review.
J Neurooncol, 2019 Oct 01
WHO grade of intracranial meningiomas differs with respect to patient's age, location, tumor size and peritumoral edema.
Mayo Clin Proc,
Monoclonal Gammopathy-Associated Peripheral Neuropathy: Diagnosis and Management.
Neurol Sci, 2021 Sep 16
Paraproteinemia and neuropathy.
Progress in neurological surgery, 2013
Stereotactic radiosurgery guidelines for the management of patients with intracranial cavernous malformations.
Pain medicine (Malden, Mass.), 2019-06-01
A Comprehensive Algorithm for Management of Neuropathic Pain.
Continuum (Minneap Minn),
Guillain-Barré Syndrome.
Obstet Gynecol Surv,
Bell's Palsy in Pregnancy.
Mayo Clin Proc,
My Treatment Approach to Giant Cell Arteritis.
J Clin Neurophysiol,
American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 Version.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2016-02
Generalized periodic discharges and 'triphasic waves': A blinded evaluation of inter-rater agreement and clinical significance.
J Clin Neurophysiol,
Atypical or Typical Triphasic Waves-Is There a Difference? A Review.
Movement disorders : official journal of the Movement Disorder Society, 2015-02
Coenzyme Q10 and spinocerebellar ataxias.
Journal of neurovirology, 2018-06
Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event.
Nutrition & metabolism, 2006-09-06
Antiepileptic drugs and bone metabolism.
Arch Neurol,
OSCILLOPSIA.
Brain : a journal of neurology, 2016-05
Association of inclusion body myositis with T cell large granular lymphocytic leukaemia.
Scand J Rheumatol, 2018 May 18
Blood-flow restricted resistance training in patients with sporadic inclusion body myositis: a randomized controlled trial.
Pacing Clin Electrophysiol,
Reproducibility of tilt table testing in patients with vasovagal syncope and its relation to variations in autonomic nervous system activity.
The Lancet. Neurology, 2016-05
Neurological prognostication of outcome in patients in coma after cardiac arrest.
Postgrad Med J,
Post lumbar puncture headache: diagnosis and management.
Anesth Essays Res,
Role of Oral Prednisolone in the Management of Postdural Puncture Headache after Spinal Anesthesia in Urological Patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993-03
Randomized prospective comparison of intraventricular methotrexate and thiotepa in patients with previously untreated neoplastic meningitis. Eastern Cooperative Oncology Group.
The New England journal of medicine, 2013-03-21
Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.
Neurology, 2013-08-13
An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke.
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