How would you approach a post-menopausal female with recurrent HR+, HER2- breast cancer with brain metastasis?
Prior localized HR+,HER2- breast cancer treated with adjuvant AC-T (5years ago)
Recent ipsilateral axillary recurrence (HR-,HER2+) s/p neoadjuvant TCHP followed by HP x 1 year
Answer from: Medical Oncologist at Academic Institution
The treatment of brain metastasis from breast cancer depends on a number of factors: number of metastases, biology of the cancer, status of extracranial disease, and performance status. From the question, it sounds like her performance status is good and she does not have progressive ext...