How would you approach a post-menopausal female with recurrent HR+, HER2- breast cancer with brain metastasis?  

Prior localized HR+,HER2- breast cancer treated with adjuvant AC-T (5years ago)

Recent ipsilateral axillary recurrence (HR-,HER2+) s/p neoadjuvant TCHP followed by HP x 1 year



Answer from: Medical Oncologist at Academic Institution