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Neuro-critical care   

Questions discussed in this category

Is there a risk of CYP2C19 gene testing only being adopted by wealthier health systems, thereby creating a disparity gap in treatment?
What is the cost and accessibility of CYP2C19 gene testing? Does the limited availability of rapid genotyping techniques limit the clinical applicabil...
3 Answers available
Does the overall conclusion of the CHANCE-2 trial make ticagrelor + ASA a worthwhile transition given the data showing cumulative hazard of stroke diverged during the first week and was subsequently similar, which suggests the benefit of ticagrelor over clopidogrel is seen predominantly soon after stroke?
4 Answers available
What is your decision process on decreasing the sodium goal for patients with cerebral edema?
1 Answer available
Would you generalize the data from the CHANCE-2 trial to a broader clinic population given that the study was specific to Han Chinese patients?
How do you plan to incorporate the results of the CHANCE-2 trial (Wang et al., PMID 34708996) in your own practice?
3 Answers available
Do you recommend genetic testing after a patient on clopidogrel has a stroke based on the results of the CHANCE-2 trial?
3 Answers available
Do you routinely obtain an EEG in patients who are admitted with traumatic intra-cerebral hemorrhage?
3 Answers available
In what conditions can you see roving eye movements?
1 Answer available
How do you complete brain death testing in patients who cannot tolerate apnea testing and are unable to transport for ancillary testing?
For instance, if the patient doesn’t tolerate apnea testing, is too unstable to go for ancillary testing outside the ICU, and TCDs/EEG are unava...
3 Answers available
How do you determine timing and frequency of stability scans for a patient with spontaneous, non-aneurysmal intracerebral hemorrhage?
What factors influence your thinking?
1 Answer available
How do you approach the management of a large vessel stroke if you anticipate the development of malignant cerebral edema?
Is there any benefit to starting hyperosmolar therapy prior to the development of depressed level of consciousness or midline shift?
1 Answer available
How do you evaluate and treat patients with cerebral edema secondary to hyperammonemia?
What modality do you prefer?
3 Answers available
When is follow-up imaging warranted in patients with anoxic brain injury?
What modality do you prefer?
1 Answer available
How do you manage autonomic storming in patients with increased intracranial pressure?
1 Answer available


Papers discussed in this category

Neurotherapeutics,
The Medical Management of Cerebral Edema: Past, Present, and Future Therapies.
The Lancet. Neurology, 2016-05
Neurological prognostication of outcome in patients in coma after cardiac arrest.
JAMA,
Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project.
Contemp Neurol Ser,
The diagnosis of stupor and coma.
N Engl J Med, 2021 Oct 28
Ticagrelor versus Clopidogrel in Loss-of-Function Carriers with Stroke or TIA.
The New England journal of medicine, 2018-07-19
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
N Engl J Med, 2013 Jun 26
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack.
N Engl J Med,
Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA.

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