Would you consider a PARP inhibitor in a patient who harbors a germline BRCA mutation who has metastatic HER2 negative gastric cancer?
Answer from: Medical Oncologist at Community Practice
There is a paucity of data in treating gastric cancer patients who harbor a gBRCA mutation with PARP inhibitors. The two published trials using olaparib in gastric cancer focused more on loss of ATM as a biomarker; while a randomized phase II study of paclitaxel +/- olaparib showed a ...
Comments
Medical Oncologist at Henry Ford Cancer Institute (HFCI) I agree that there are no data to support use of P...
I agree that there are no data to support use of P...