When do you consider testing for dihydropyrimidine dehydrogenase (DPD) for patients prior to treatment with 5-FU/capecitabine?

Topics: Gastrointestinal Cancers • Medical Oncology • Supportive Care

If you do test, do you have a preferred testing method?

Answer from: Medical Oncologist at Community Practice

Happy to address this question! It is my practice to test for DPD deficiency in all patients who will receive a first treatment with a fluoropyrimidine agent (5-FU or capecitabine). My objective in doing this is to avoid infrequent but readily avoidable severe toxicities and deaths related to DPD de...

Comments

Medical Oncologist at Tower Health Medical Group
Great review!

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