What clinical scenarios would one prefer long course chemoradiation compared to short course radiation in locally advanced rectal cancer as part of a total neoadjuvant therapy approach?

Topics: Radiation Oncology • Gastrointestinal Cancers

Answer from: Radiation Oncologist at Academic Institution

A great question that we discuss at tumor board often which I think really highlights the need for multidisciplinary care of rectal cancer. Recent data from RAPIDO (Bahadoer et al., PMID 33301740) has demonstrated efficacy of total neoadjuvant therapy (TNT) with short course radiation therapy follow...

Comments

Radiation Oncologist at Lake Huron Medical Center
Very comprehensive answer! Do you think that 45/2...

Radiation Oncologist at Ohio State University James Cancer Hospital and Solove Research Institute
That is a good point, Dr. @Simul Parikh. For acute...

Radiation Oncologist at Lake Huron Medical Center
Sure, that makes sense. At the same time, BED wise...

Radiation Oncologist at Ohio State University James Cancer Hospital and Solove Research Institute
Yes, agree. I've found that if you take some extra...

Radiation Oncologist at Karmanos Cancer Institute - McLaren Proton Therapy Center
Lately, we've been doing TNT with chemoRT followed...

Radiation Oncologist at Veterans Affairs
Appreciate the conversation as we continue to iden...

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