Is a carboplatin-based regimen a reasonable alternative for patients with muscle-invasive bladder cancer who are not eligible for neoadjuvant cisplatin-based chemotherapy?
Answer from: Medical Oncologist at Academic Institution
The data supporting the use of neoadjuvant chemotherapy for bladder cancer is derived from 2 randomized trials and a meta-analysis. The randomized trials demonstrating benefit used MVAC and CMV, respectively, both cisplatin-based combinations. The meta-analysis results support the use of neoadj...
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