How would you treat a locally recurrent triple negative breast cancer after achieving CR a year earlier to neoadjuvant ddAC-T, BCS and WBRT?
Would you consider use of immunotherapy with checking PDL1? What chemotherapy agents would you consider along with mastectomy/radiation?
Answer from: Medical Oncologist at Community Practice
I would recommend staging work up to rule out distant metastases for this patient with high-risk TNBC before committing this patient to local therapy.Isolated Loco-regional recurrences (ILRR) are associated with a high risk of developing distant metastases and early recurrence (< 24 months, as in...
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