How would you approach an elderly patient with locally advanced breast cancer and co-morbidities, who strongly refuses surgery but is willing to consider radiation?

Topics: Breast Cancer • Radiation Oncology

Answer from: Radiation Oncologist at Academic Institution

Presuming that this is nonmetastatic, if the local symptoms permit, I would prioritize starting with systemic therapy to cytoreduce, then treat with a hypofractionated regimen, with the understanding that this is a palliative approach if surgery is refused. This is (obviously) a very general "first ...

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Radiation Oncologist at Duke University Medical Center
For a variety of reasons, some valid and others le...

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