How do you incorporate radiation therapy in patients undergoing CAR T-cell therapy for DLBCL?
Answer from: Radiation Oncologist at Community Practice
It depends on the circumstances of the patient, but there are three emerging indications for RT in the setting of CAR T-cell therapy:
Tumor debulking prior to CAR T-cell infusion
Bridging therapy between apheresis and CAR T-cell infusion
Salvage of refractory, progressive or relapsed disease fo...
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Answer from: Medical Oncologist at Academic Institution
Chimeric antigen receptor (CAR) T-cell therapy has been approved by the US Food and Drug Administration and other regulatory agencies for patients with R/R DLBCL (including high-grade B-cell lymphoma, primary mediastinal B-cell lymphoma, and transformed follicular lymphoma) after 1-2 prior lines of ...