How do you determine the optimal duration of bevacizumab therapy for treatment of brain radionecrosis following SRS?
Answer from: Radiation Oncologist at Community Practice
I would recommend enrolling patients on the randomized trial from Alliance, A221208 which randomizes patients to dexamethasone +/- bevacizumab. In that protocol, bevacizumab is given on days 1 & 15 of a 28-day cycle x 4 cycles.
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