How do you approach HER2 directed therapy with discrepant results between FISH and Oncotype?

Topics: Breast Cancer • Medical Oncology • Her2+

Especially if HER2 negative on pathological specimen

Answer from: Radiation Oncologist at Community Practice

At our institution, we don’t do Oncotype for HER2+ (by IHC or FISH) cases. See our published data showing the discrepancy.

Comments

Medical Oncologist at Stanford University, School of Medicine
Thank you so much for sharing this data!

Medical Oncologist at Joliet Oncology - Hematology Associates, Ltd.
What do you do if FISH is negative but oncotype is...

Radiation Oncologist at Varian Medical Systems/Allegheny health network
This is a very rare event and we have not changed ...