For muscle-invasive bladder cancer with predominant (>90%) squamous differentiation, would you consider cisplatin-based neoadjuvant chemotherapy prior to radical cystectomy or upfront surgery?

Topics: Genitourinary Cancers • Bladder Cancer • Medical Oncology • NCI-CCC Tumor Board Question • UCSF • NCI-CCC GU Tumor Board Question

Would a PET avid pelvic lymph node without distant metastatic disease change your management?

Answer from: Medical Oncologist at Community Practice

While muscle-invasive bladder cancer (MIBC) patients with a minor variant histology component are treated similarly to conventional urothelial carcinoma (i.e., neoadjuvant cisplatin-based combination followed by surgery), there are no definitive data to guide the perioperative systemic therapy of th...

Comments

Medical Oncologist at Tower Health Medical Group
Great review. Thank you!!

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