Rheumatology

Neuro-immunology

Questions discussed in this category

When do you consider tapering tocilizumab in patients with GCA in remission?

1 Answer available

In what patients would you consider adjunctive IVIG for Sjogren's-related neuropathy?

2 Answers available

When would you consider checking JC virus prior to initiating biologic therapy?

1 Answer available

What is your steroid-sparing agent of choice to treat GCA given the current tocilizumab shortage?

Thoughts on sarilumab vs methotrexate, or just treat with steroids alone

1 Answer available

What is your approach to checking serum vWF antigen levels in adult patients with CNS vasculitis for monitoring disease activity?

Small study in pediatric PACNS have evaluated this as a potential marker (Cellucci et al., PMID 22740622)

1 Answer available

What therapies have you had the most success with for calcinosis cutis in dermatomyositis patients?

1 Answer available

Do you treat HIV/AIDS-associated CNS vasculitis with antiretrovirals alone or in combination with steroids?

1 Answer available

Papers discussed in this category

Front Neurol, 2019 Jun 06

Primary Angiitis of the Central Nervous System: New Potential Imaging Techniques and Biomarkers in Blood and Cerebrospinal Fluid.

N Engl J Med,

Trial of Tocilizumab in Giant-Cell Arteritis.

Lancet, 2016 Mar 04

Tocilizumab for induction and maintenance of remission in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial.

Arthritis Rheum,

Adjunctive methotrexate for treatment of giant cell arteritis: an individual patient data meta-analysis.

Journal of neurovirology, 2018-06

Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event.

Muscle & nerve, 2007-01

Rituximab treatment in patients with IVIg-dependent immune polyneuropathy: a prospective pilot trial.

Annals of neurology, 1990-03

Ataxic sensory neuropathy and dorsal root ganglionitis associated with Sjögren's syndrome.

Rheum Dis Clin North Am, 2017 Aug 23

Neurologic Manifestations of Primary Sjögren Syndrome.

Neurology,

Benefit of IVIG for long-standing ataxic sensory neuronopathy with Sjögren's syndrome. IV immunoglobulin.

Medicine (Baltimore),

Sjögren Sensory Neuronopathy (Sjögren Ganglionopathy): Long-Term Outcome and Treatment Response in a Series of 13 Cases.

Muscle Nerve, 2014 Dec 23

Sensory ganglionopathy with livedoid vasculopathy controlled by immunotherapy.

Arthritis Care Res (Hoboken), 2020 May 19

Prevalence of Giant Cell Arteritis Relapse in Patients Treated With Glucocorticoids: A Meta-Analysis.

J Rheumatol, 2021 Feb 15

Real-world Risk of Relapse of Giant Cell Arteritis Treated With Tocilizumab: A Retrospective Analysis of 43 Patients.

Rheumatology (Oxford),

Risk of relapse after discontinuation of tocilizumab therapy in giant cell arteritis.

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