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Rheumatology
Methotrexate
Questions discussed in this category
In the absence of lung disease, do you prefer methotrexate or mycophenolate mofetil in the initial treatment of cutaneous-only manifestations in systemic sclerosis?
2 Answers available
How do you approach folate supplementation for methotrexate-related side effects?
3 Answers available
What is your methotrexate initiation strategy in DMARD-naive RA patients?
Specifically: starting dose, rapidity of up-titration, frequency of lab monitoring, frequency of office visits, and timing of assessment for treatment...
2 Answers available
What is your threshold for number of alcoholic drinks per week before reconsidering prescribing methotrexate/leflunomide?
1 Answer available
Do you continue methotrexate in inflammatory arthritis patients who develop squamous cell skin cancer while on that therapy?
1 Answer available
How would you manage methotrexate therapy in an active rheumatoid arthritis patient undergoing treatment for latent TB with rifampin?
Do you stop methotrexate or adjust the dose?
1 Answer available
How would you treat uveitis in a patient with a history of cutaneous T cell lymphoma?
Patient was previously well controlled on methotrexate, which was discontinued during cancer treatment.
1 Answer available
Should MTX be avoided in RA patients with asymptomatic lung nodules?
If so, what would be an ideal DMARD in this setting?
1 Answer available
Should tuberculosis screening be performed before beginning methotrexate for treatment of rheumatoid arthritis?
1 Answer available
How do you assess transaminitis in a patient with sarcoidosis with known liver involvement being treated with methotrexate?
1 Answer available
Should methotrexate be categorically avoided in RA patients with COPD or RA-ILD?
1 Answer available
Should patients be screened for hepatitis B/C prior to starting a conventional synthetic DMARD such as methotrexate?
1 Answer available
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Papers discussed in this category
Semin. Arthritis Rheum., 2020 Mar 19
RISE registry reveals potential gaps in medication safety for new users of biologics and targeted synthetic DMARDs.
Archives of internal medicine, 2008-09-22
Methotrexate is not associated with progression of interstitial lung disease in rheumatoid arthritis.
Arthritis and rheumatism, 2010-06
Incidence and mortality of interstitial lung disease in rheumatoid arthritis: a population-based study.
Cochrane Database Syst Rev, 2013 May 31
Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis.
Ann Rheum Dis, 2017 Mar 23
Quantifying the hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis taking methotrexate.
Related Topics in Rheumatology
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Radiation Oncology
Gynecologic Cancers
Palliation
Neuro-Oncology
Genitourinary Cancers
Melanoma/Skin Cancer