Rheumatology

Inflammatory eye disorders

Questions discussed in this category

How do you decide on a steroid sparing agent for idiopathic orbital inflammation partially responsive to steroids?

1 Answer available

How would you treat corneal melt (in the absence of peripheral arthritis) in rheumatoid arthritis?

What immunosuppression and dosing do you typically use?

1 Answer available

In a patient with inflammatory orbital disease without a discrete mass to biopsy and recent bisphosphonate use, how much additional workup would you do if basic labs, urine studies, ANCA serologies, thyroid studies, chest imaging (to r/out sarcoid) are normal, before concluding that the process is likely secondary to bisphosphonate use?

Without a discrete mass to biopsy, is there any utility of any blind biopsies to rule out IgG4 related disease, infectious or neoplastic process?

1 Answer available

What do you use to treat uveitis refractory to conventional synthetic DMARDs and TNF inhibitors?

Are IL-17 or IL-23 inhibitors helpful?

5 Answers available

How would you treat uveitis in a patient with a history of cutaneous T cell lymphoma?

Patient was previously well controlled on methotrexate, which was discontinued during cancer treatment.

1 Answer available

Do you extrapolate from uveitis treatment pathways when managing other inflammatory eye conditions such as atypical serpiginous choroiditis?

2 Answers available

Are there any situations in which you would consider starting steroid-sparing agents at the outset for patients with scleritis without any evidence of systemic rheumatic disease?

2 Answers available

Papers discussed in this category

Ophthalmology, 2015-05

Efficacy and safety of intravenous secukinumab in noninfectious uveitis requiring steroid-sparing immunosuppressive therapy.

Retina,

LONG-TERM OUTCOMES OF RITUXIMAB THERAPY IN PATIENTS WITH NONINFECTIOUS POSTERIOR UVEITIS REFRACTORY TO CONVENTIONAL IMMUNOSUPPRESSIVE THERAPY.

Ophthalmic Res, 2018 Apr 10

Cyclophosphamide or Rituximab Treatment of Scleritis and Uveitis for Patients with Granulomatosis with Polyangiitis.

Dev Ophthalmol, 2012 Apr 17

Rituximab for noninfectious uveitis.

Arthritis Rheumatol, 2019 Aug 12

Long-Term Outcome of Ustekinumab Therapy for Behçet's Disease.

American journal of ophthalmology, 2017-11

Primary (Month-6) Outcomes of the STOP-Uveitis Study: Evaluating the Safety, Tolerability, and Efficacy of Tocilizumab in Patients With Noninfectious Uveitis.

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