Rheumatology   

Do you base the decision on FEV1, 6MWD or symptoms at initial evaluation, or progression over time?

Assuming other non CTD related causes for PAH have been excluded

Would you suggest switching to a viral vector vaccine, such as J&J?

Would you discontinue Methotrexate and TNF inhibitors even if previously no side effects from these medications, and would you consider Cyclophosphami...

While classically described as seen in seropositive patients, have they been reported in seronegative RA?

Would you have a different opinion based on whether it is a new therapy or an existing and previously well-tolerated therapy for the patient?

Do you use imaging (fibrosis vs. pneumonitis), PFTs, duration of prior immunosuppressive therapy?

Would you change rituximab maintenance dose or schedule?

How is your approach to treatment different than other ILD patterns such as NSIP? Does treatment response vary based on underlying CTD?

Cyclophosphamide/tacrolimus and Rituximab have been used in conjunction with steroids in case series.

If so, what would be an ideal DMARD in this setting?

 If you use both, how do you decide which to use for a particular patient?

The SENSCIS trial was published in 2019 on efficacy of this agent. However, it's not clear where this should be in the treatment algorithm: Monot...

Is IO related pneumonitis in the radiation field or more diffuse?