Questions discussed in this category
How does graft function play into your decision making? How do you utilize post allogeneic transplant chimerism in clinical practice? Do you obta...
How does belumosudil now fit in your approach to steroid refractory chronic graft-versus-host disease?
Are there major differences in standard conditioning and/or GVHD prophylaxis regimens utilized?
Does the non-relapse mortality different significantl...
Such as patients who are frail, elderly, renally impaired?
Would you consider sirolimus over cyclosporine or tacrolimus for safer nephrotoxicity prof...
If given both options, which donor would one prefer: haploidentical related donor or 7/8 mismatched unrelated donor using post transplant cyclophospha...
Both the patient's nasopharyngeal swab and stem cells themselves resulted COVID positive post-harvesting.
Adults tend to do this procedure earlier in the course, but it is unclear when it is appropriate for a pediatric patient, and is often considered too ...
Do you always treat with the full 21-day treatment course, or can defibrotide be stopped if certain criteria are met sooner?
Would you test for bone marrow failure syndromes before beginning the conditioning regimen?
Or do you use prophylactic defibrotide?
I have heard <20% MRD. What about proceeding if patient is hypoplastic after chemotherapy?
Would you consider “bridging” therapy with something like an HMA?
What dose do you recommend?
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Papers discussed in this category
Cancer, 2004-08-15
Br. J. Haematol., 2003-11-01
Br. J. Haematol., 1998-08-01
Cancer, 1990-11-15
Radiother Oncol, 1990-01-01
Clin Lymphoma Myeloma Leuk, 2017 Mar 07
Bone Marrow Transplant, 2019 Oct 01
Front Immunol, 2020 Apr 03
Bone Marrow Transplant,
Lancet Haematol, 2021 Feb 01
Transfusion, 2020 May 27
Vox Sang, 2020 Apr 21
Lancet, 2020 Feb 12
Transplant Cell Ther, 2021 Sep 02
Blood Adv,
Front Oncol, 2021 Mar 25
Regen Ther, 2020 May 15
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015-04
Pediatr Blood Cancer, 2019 Jul 31
J Clin Oncol, 2021 Dec 9
Blood Cancer Discov, 2021 Dec 01