Questions discussed in this category
Assuming minimal toxicities except fatigue from long, recurrent infusions.
Do you include pembrolizumab with platinum-taxane + bevacizumab or reserve it as a second line option?
Do you try to keep Hb> 10 or 12? Or somewhere in between?
Previously received pelvic EBRT and intracavitary brachytherapy. IORT was administered to the node-positive side wall at the time of exenteration.
Initially treated with definitive chemoRT but recurred with distant mets. Completed 6 cycles carb/tax/bev with minimal toxicity. Excellent performance...
Lung is biopsy proven met cervix, SBRT is planned.
Patient did not previously receive para-aortic radiation. Considering RT vs RT + chemo vs chemo alone
Recurrence was 2cm and PET confirmed local. Excision with positive margins. Current plan for salvage whole pelvic RT and vaginal cuff brachytherapy +/...
If confirmed neuroendocrine and PD-L1 pending, how would you treat?
This has been a common practice in the community. Is there a benefit for certain patients?
Would you be more or less likely to use a cisplatin-containing regimen if a patient had previously responded to chemoradiation with concurrent cisplat...
Does the phase II KN-158 provide sufficient evidence to change management?
Should this be done at the time of recurrence or after failure of 1st line therapy for recurrence?
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Papers discussed in this category
JAMA Netw Open, 2021 Apr 01
Clinical cancer research : an official journal of the American Association for Cancer Research, 2015-12-15
J. Clin. Oncol., 2011 Mar 28
BMC Cancer, 2017 Apr 28
N. Engl. J. Med.,
Lancet (London, England), 2017-10-07
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019-06-10
J Clin Oncol, 2019 Nov 04
Lancet Oncol, 2021 Apr 09
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000-04
Gynecologic oncology, 1998-08
Gynecologic oncology, 2011-07
BMC Cancer, 2018 May 04
Gynecol Oncol, 2017 Sep 24
N Engl J Med, 2021 Sep 18
N Engl J Med, 2022 Jan 19