Hematology

Anemia

Questions discussed in this category

How soon do you anticipate response to cyclosporine in red cell aplasia and what cyclosporine trough levels do you target?

1 Answer available

Does normal methylmalonic acid levels absolutely rule out vitamin B12 deficiency?

1 Answer available

How do you manage patients who develop minor antigen antibodies and require multiple blood transfusions?

e.g. K, Fya, s, etc

1 Answer available

Would you retry rituximab in steroid refractory warm autoimmune hemolytic anemia which responded to rituximab before?

Last rituximab 6 months ago

1 Answer available

Would you check vitamin B6 routinely in the work up of anemia?

1 Answer available

Do you routinely check for copper deficiency as part of workup for bicytopenia with leukopenia/anemia or pancytopenia?

1 Answer available

In your practice, do you usually check MMA and B12 simultaneously or start with B12 levels and check MMA only if indeterminate?

1 Answer available

Would you offer a complement inhibitor to a minimally symptomatic PNH patient with mild non-transfusion dependent hemolytic anemia?

1 Answer available

Do you routinely obtain bone marrow biopsy in newly diagnosed autoimmune hemolytic anemia when working up potential underlying etiologies?

1 Answer available

What is the transfusion management of a sickle cell patient during pregnancy?

What are your target goals during transfusion, either prophylactically or during acute complication? Does your management change between vaginal deliv...

1 Answer available

Would you recommend use of ESA for anemia of kidney disease in the setting of metastatic solid tumor malignancy?

1 Answer available

How do you approach transfusing a patient with sickle cell disease who has a history of hyperhemolysis?

1 Answer available

How can healthcare providers better serve as allies of the sickle cell community?

Has your medical practice taken any steps either in community outreach or within the clinic to show support for this medically vulnerable population, ...

2 Answers available

How do you workup erythrocytosis with a normal or elevated serum erythropoietin?

2 Answers available

How do you approach the management of a patient with symptomatic iron deficiency anemia who is intolerant of iron?

Such as a patient who cannot tolerate oral iron and has had a anaphylaxis to intravenous iron

4 Answers available

When would you consider splenectomy or other immunosuppressive/cytotoxic therapy for steroid-refractory warm autoimmune hemolytic anemia?

For example, in a patient who is steroid-refractory, requiring regular transfusion, and has not had response to rituximab after several weeks.

1 Answer available

Papers discussed in this category

Blood, 2015-05-28

How I treat and manage strokes in sickle cell disease.

Blood Adv, 2020 Jan 28

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support.

Blood, 2015 Aug 24

Prophylactic transfusion for pregnant women with sickle cell disease: a systematic review and meta-analysis.

Leukemia, 2009-05

The complete evaluation of erythrocytosis: congenital and acquired.

Am J Prev Med,

Population estimates of sickle cell disease in the U.S.

J Natl Med Assoc,

Health-related stigma in young adults with sickle cell disease.

J Adv Nurs, 2015 Sep 09

Perceptions of young adults with sickle cell disease concerning their disease experience.

Issues Ment Health Nurs, 2018 Apr 13

Stigma of Sickle Cell Disease: A Systematic Review.

JAMA Netw Open, 2020 May 01

Perceptions of US Adolescents and Adults With Sickle Cell Disease on Their Quality of Care.

Emerg Infect Dis, 2020 Jul 08

Coronavirus Disease among Persons with Sickle Cell Disease, United States, March 20-May 21, 2020.

Transfus Med Rev,

Treatment with intravenous immunoglobulin and steroids may correct severe anemia in hyperhemolytic transfusion reactions: case report and literature review.

Am J Kidney Dis, 2019 Aug 05

The Use of Erythropoiesis-Stimulating Agents in Patients With CKD and Cancer: A Clinical Approach.

Br J Haematol, 2013 Aug 02

A multi-centre retrospective study of rituximab use in the treatment of relapsed or resistant warm autoimmune haemolytic anaemia.

Blood, 2019 Apr 25

Transfusion-related red blood cell alloantibodies: induction and consequences.

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