Dermatology

Melanoma/Skin Cancer   

Questions discussed in this category



If not, what tumor characteristics prompt you to collect debulking specimens for paraffin or frozen section staining? 

In a patient who would be otherwise fit for surgery +/- adjuvant RT, and the delay is caused by COVID-related OR staffing issues, what would be your a...

Is there any alteration in approach from the medical, surgical, or radiation oncology perspective that can mitigate the risk of forming keloids withou...

What is the role and sequence of surgery and/or RT? Which nodal levels would you include in your RT field(s)?

What approaches (surgical vs non-surgical) offer the best cosmesis for keratoacanthoma (low grade squamous cell carcinoma) ? 

Is there a role for radiation? Does your approach differ depending on site(s) of  disease, and/or if the patient has Basal-Cell Nevus (Gorlin) sy...

In general, how would you approach such a case with regards to creation of your treatment volumes and dose-fractionation? 

Would you recommend radiation therapy or immunotherapy? If proceeding with radiation therapy, what dose-fractionation and technique would you utilize?

When do you electively treat the ipsilateral versus ipsi- and contralateral neck?

This particular case involves a patient with a frontal scalp low grade eccrine carcinoma status-post excision with positive margin complicated by...

Would you treat the primary site alone, include the hand and arm lymphatics to the epitrochlear nodes (one continious treatment volume from hand to el...

Given the location but no other high risk features would you offer RT?  If so, what dose and fields? 

What pathologic features are most important when evaluating the possible need for adjuvant therapy?

*Negative margins, <1cm in size, no LVI, negative SLNB, not immunocompromised, no prior surgery (as well as a negative PET/CT scan).

NCCN lists only substantial perineural invasion.  What about other high-risk adverse features such as histologic subtype, multiple recurrences, d...

When elective nodal radiation is recommended, which nodes would you treat (i.e. facial, pre-auricular, peri-parotid, levels I-III, etc.)?

Patient underwent a shave biopsy of a 6x5x2mm preauricular lesion that showed moderatley differentiated sebaceous carcinoma with deep and lateral marg...

What dose/fractionation would yield the lowest risk of graft failure? Does your treatment management change based of location, ex the ear vs back?

If so, how large of a margin would you place on the primary lesion and would you incorporate any adjacent lymph node levels?

Following Mohs surgery and in the absence of other high risk features, do you offer RT for any PNI?  A single nerve < 0.1 mm? A single ne...

Would re-irradiation be an appropriate option? What dose/field would you incorporate? If treating with standard fractionation, would you take the enti...

I have seen some patients who may undergo large complex closures (sometimes as a separate procedure) for smaller lesions with resulting scars that sig...

Is modern surgical/reconstruction treatment superior to radiation therapy? If contact brachytherapy or superficial (orthovoltage) therapy isnt possib...


Papers discussed in this category


Cancer, 1995 May 1

Ann Surg Oncol, 2003 May

American journal of surgery, 2001-12

World J Surg, 1992 Mar-Apr

Cancer, 2005-10-01

Journal of contemporary brachytherapy, 2017-04

Melanoma research, 2015-04

Nature, 2018-01-18

Cureus, 2019 Jun 18

PloS one, 2015

The British journal of dermatology, 2019-02

JAAD Case Rep, 2019 Jun 26

Pract Radiat Oncol, 2019 Dec 09

Lancet Oncol, 2019 Dec

Journal of medical case reports, 2010-05-22

Ann Med Surg (Lond), 2017 Jun 20

Case Rep Oncol, 2021 May 10

J Clin Oncol,

Journal of the American College of Surgeons, 2011-04

Am J Surg,

Dermatol Clin,

J Am Acad Dermatol, 2014 Sep 19

Br J Dermatol,

East Afr Med J,

Int J Dermatol,

J Pathol,

Sci Rep, 2021 Oct 12

Acta Derm Venereol,

Br J Dermatol, 2019 Sep 18

Br J Dermatol, 2019 Oct 16

The American Journal of dermatopathology, 2013-07

The American journal of surgical pathology, 2018-03

The American journal of surgical pathology, 2018-11

Appl Immunohistochem Mol Morphol,

Pathology, 2016 Aug 28

Am J Dermatopathol,

Am J Dermatopathol,

J Am Acad Dermatol, 2022 Jun 23

Dermatol Surg,